There is some info missing to get a good answer for this question. What are you using to diffuse the CO2 into the water? The more effecient the system the lower the bubble rate you will need. If you are using a reactor then o.5 to 1.o bps should be enough as this is very efficient. Although the bps thing is not always very accurate due to different bubble sizes from different needle valves.
The drop checker is your most important tool in regulating the CO2 in the tank. Are you using 4dkH reference solution in your drop checker? If you are using just tank water then it may throw off the pH in the solution due to other substances in the water.
The best thing to do is start with a bps that you feel is good for the method that you are using and within 2 hours you will be pretty close to the saturation point that can be reached in your tank. Watch it for the day and adjust as needed. I wouldn't worry a lot about the fish as you will need to seriously over dose CO2 in order to kill them before they start to show signs of being uncomfortable.
The drop checker is your most important tool in regulating the CO2 in the tank. Are you using 4dkH reference solution in your drop checker? If you are using just tank water then it may throw off the pH in the solution due to other substances in the water.
The best thing to do is start with a bps that you feel is good for the method that you are using and within 2 hours you will be pretty close to the saturation point that can be reached in your tank. Watch it for the day and adjust as needed. I wouldn't worry a lot about the fish as you will need to seriously over dose CO2 in order to kill them before they start to show signs of being uncomfortable.