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I had problems with my shrimps dying(3-7 a day). All my water params were just fine. With advise from others, I did a 50% wc and then dosed with a double dose of Prime. I have had no problems since. It could be minerals in the water that your normal water conditioner isn't getting or it isn't getting all of it out of the water.
As far as ammonia or nitrite spikes, wc will help remove them.
 
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