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I do the 30 minutes before thing on a 65gl, no problems. Some worry about the ph change but it only represents gas exchange.

I have about 3wpg and it's a pain to deal with even running an inline reactor. I'd guess you'll be using that Excel, I am. Depends on your particular light/ photoperiod and what your stocking is I guess, my fish won't allow me to crank anymore gas than about 5bps.
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